Which drugs cause gynaecomastia

Tests may include liver, renal and thyroid function Medicines may cause gynaecomastia through a number of mechanisms including: 4,5.

Many commonly prescribed medicines have been reported to cause gynaecomastia 5. Table 1 provides examples of medicines that have been associated with gynaecomastia 2,3. Table 1: Medicines reported to be associated with gynaecomastia [this is not an exhaustive list] Good: Systematic review of randomised controlled trials, randomised placebo controlled trial, or prospective cohort studies with or without concurrent controls plus good pathophysiological explanation.

Fair: Retrospective studies, case-control studies or case series with good pathophysiological explanation. Other reported non-medicine causes of gynaecomastia include alcohol, amphetamines, heroin, marijuana cannabis and phytoestrogens in some herbal medicines 2,3,4,7. Up to 30 June , reports of gynaecomastia suspected to be caused by medicines have been reported to CARM 4. Risk of gynaecomastia associated with cimetidine, omeprazole, and other antiulcer drugs.

BMJ ; Wolfe CJ. Case report. Gynecomastia following digitalis administration. J Fla Med Assoc ; Efavirenz directly modulates the oesterogen receptor and induces cancer cell growth. HIV Med ; Green GR.

Mechanism of hypogonadism in cirrhotic males. GUT ; Eli C. Ketoconazole binds to the human androgen receptor. Horm Metab Res ; Overview Enlarged breasts in men gynecomastia Open pop-up dialog box Close. Enlarged breasts in men gynecomastia With gynecomastia, tissue inside the breast glands grows. Request an Appointment at Mayo Clinic.

Share on: Facebook Twitter. Show references Fentiman IS. Managing male mammary maladies. European Journal of Breast Health. Braunstein GD, et al. Epidemiology, pathophysiology, and causes of gynecomastia.

Accessed Aug. Sansone A, et al. Gynecomastia and hormones. Jameson JL, et al. Disorders of the testes and male reproductive system. In: Harrison's Principles of Internal Medicine. The McGraw-Hill Companies; Papadakis MA, et al. Endocrine disorders. McGraw-Hill Education;